Ubiquitination in the regulation of autophagy

Autophagy, an efficient and effective approach to clear rapidly damaged organelles, macromolecules, and other harmful cellular components, enables the recycling of nutrient materials and supply of nutrients to maintain cellular homeostasis.Ubiquitination plays an Felt Toy important regulatory role in autophagy.This paper summarizes the most recent

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Estimation of community-wide multi-chemical exposure via water-based chemical mining: Key research gaps drawn from a comprehensive multi-biomarker multi-city dataset

This paper explores the strong potential of chemical mining of wastewater for markers of community-wide intake of wide-ranging harmful chemicals belonging to several usage Protective oil groups: industrial chemicals, personal care products, pesticides, illicit drugs, lifestyle chemicals and prescription pharmaceuticals as a proxy for multi-chemical

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Parasitic success and venom composition evolve upon specialization of parasitoid wasps to different host species

Female endoparasitoid wasps usually inject venom into hosts to suppress their immune response and ensure offspring development.However, the Umbrella parasitoids ability to evolve towards increased success on a given host simultaneously with the evolution of the composition of its venom has never been demonstrated.Here, we designed an experimental e

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Automated high-throughput quantification of mitotic spindle positioning from DIC movies of Caenorhabditis embryos.

The mitotic spindle is a microtubule-based structure that elongates to accurately segregate chromosomes during anaphase.Its position within the cell also dictates the future cell cleavage plan, thereby determining daughter cell orientation within a tissue or cell fate adoption for polarized cells.Therefore, the mitotic spindle ensures at the same t

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